ENKORE Workshop: Advancing Adverse Outcome Pathways (AOP) Frameworks for Endocrine Disruption Research

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The ENKORE cluster invites researchers, regulatory experts, and students to join the upcoming workshop “Advancing Adverse Outcome Pathways (AOP) Frameworks for Endocrine Disruption Research.”

This workshop is the first in a series of four thematic ENKORE workshops designed to strengthen scientific collaboration and knowledge exchange across the cluster’s partner institutions.

Participants can choose between sessions tailored to different experience levels—from beginners to advanced AOP users and developers. Each session will be guided by leading experts from ENKORE partners, the Society for the Advancement of Adverse Outcome Pathways (SAAOP), the Joint research center (JRC) of the European Commission, and the OECD – OCDE.

The full programme runs for a total of 5 hours, but participants may register only for the sessions most relevant to their expertise and interests.

Block your calendar to explore innovative ways of applying AOP frameworks in endocrine disruption research and contribute to advancing the scientific understanding of chemical safety in Europe.

 

Agenda

11:00 – Opening Remarks

Welcome and brief introduction about the cluster and online workshop

11:05 – Session 1: Basics about the AOP framework

Topics: Overview of the Adverse Outcome Pathway (AOP) framework and its scientific foundation, The OECD AOP Coaching Program

Speakers:

  • Daniel Villeuenve, USEPA, SAAOP (former president), co-founder of the AOP framework
  • Shihori Tanabe, National Institute of Health Sciences Japan, OECD AOP coach lead

12:30 – Session 2: (q)AOP development strategies

Topics: Leveraging AI tools and OMICs data to enhance AOP development, Innovative approaches to strengthen regulatory acceptance of AOPs, quantitative AOPs

Speakers:

  • Siegfried Morath, JRC
  • Alexandra Schaffert, Tampere University, SAAOP
  • Clemens Wittwehr, JRC, SAAOP
  • You Song, NIVA, SAAOP (councellor), OECD AOP coach, ENKORE AOP WG co-chair

13:45– Lunch break

14:30 – Session 3: Success stories of the AOP framework: from development to regulatory applications

Topics: Real-world examples of successful AOPs and their impact on science and policy.

Speakers:

  • Nathalie Delrue, OECD
  • Terje Svingen & Anna Beronius, DTU & KI, PARC
  • Dries Knapen, University of Antwerp, SAAOP president, lead of PARC AOP/IATA work
15:25 – Session 4: Flash introductions on AOP-related work in ENKORE cluster

Topics: Short presentations showcasing ongoing AOP-related initiatives within the ENKORE cluster.

Details

Start

11 December 2025
11:00

End

16:00

Location

Online

Registration

EN FundedbytheEU RGB POS
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